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The Journal of Clinical Investigation

doi: 10.1007/978-3-319-43238-0_5 31 WentzAC

Mark Haupt, MD, shares insights from his work in research, academia, and the pharmaceutical industry

(2007) This foundational laboratory study demonstrated that the related peptide AHK-Cu directly stimulates hair follicle elongation and protects dermal papilla cells from apoptosis (caspase-3 reduced 42.7%, PARP reduced 77.5%)

Subsequent research has indicated that PMFs and HPMFs can diminish adipocytes in perigonadal fat by downregulating adiponectin 1 protein, and sterol regulatory element binding protein 1 (SREBP-1) expression in obese mice